Abstract
Multidrug resistance bacteria causing urinary tract infections have become a more serious concern nowadays. Grampositive and gram-negative bacteria are involved in causing urinary- tract infections, and it is more frequent in females as compared to males. Nowadays, there is increasing in antibiotic resistance to almost all available antibiotics, which has become a major therapeutic issue. So, finding ethnomedicinal plants for the treatment of various kinds of infection is a priority. The study aims to assess the antibacterial properties of 3 tropical plants (Psidium guajava, Syzygium cumini, and Punica granatum) for possible use as antibacterial agents against 4 isolated MDR bacteria (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus). Antibiograms of isolated bacteria were detected by disc- diffusion method, and the antibacterial activity of ethnomedicinal plants was detected by the agarwell diffusion method. Methanol and n-hexane extracts from these 3 plants were used for this study. These 3 ethnomedicinal plants were found to be at least showing 16- 21 mm as a zone of inhibition in lawn culture. Minimum inhibitory concentration and Minimum bactericidal concentration of methanol extracts of 3 plants were recorded. The methanol extract of Psidium guajava, Punica granatum, and Szygium cumini was found to be effective, but Szygium cumini was found to be more effective as compared to the Psidium guajava and Punica granatum.
Keywords: Escherichia coli, Klebsiella pneumoniae, Multidrug Resistance Bacteria, Pseudomonas aeruginosa, Urinary Tract Infection